Safety and preliminary results of perioperative chemotherapy and hyperthermic intraperitoneal chemotherapy (HIPEC) for high-risk gastric cancer patients

Table 1 Toxicity profile of patients treated with perioperative and hyperthermic intraperitoneal chemotherapy

Event	Grade 3/4
	Preoperative chemotherapy			Postoperative chemotherapy
	1	2	3	1	2	3
Adverse events, n/total	5/10	3/10	1/10	2/10	2/10	6/10
Grade 3/4 events	4/10	3/10	1/10	2/10	0/10	2/10
Non-hematological toxicity	3	3	1	2	0	1
Fatigue	0	0	0	0	0	0
Anorexia	0	1	0	0	0	0
Gastrointestinal	1	2	1	2	0	1
Mucositis	2	0	0	0	0	0
Rash	0	0	0	0	0	0
Alopecia	0	0	0	0	0	0
Fever	0	0	0	0	0	0
Hematological toxicity	1	0	0	0	0	1
Pancytopenia	0	0	0	0	0	0
Neutropenia	1	0	0	0	0	1
Total events	4	3	1	2	0	2

Results are presented as number of patients. Hematological toxicity was evaluated according to CTCAE v4.0. All grade 3/4 adverse events are described in Table 1.

ISSN: 1477-7819