From: Expression and significance of the TLR4/MyD88 signaling pathway in ovarian epithelial cancers
TLR4/MyD88 | TLR4/MyD88/NF-κB | ||||||
---|---|---|---|---|---|---|---|
Positive | Negative | P | Positive | Negative | P | ||
Histologic type | Serous | 12 | 48 | 0.000 | 10 | 50 | 0.002 |
Mucinous | 2 | 23 | 1 | 24 | |||
Endometrioid | 2 | 9 | 2 | 9 | |||
Clear cell | 13 | 12 | 12 | 13 | |||
Undifferentiated | 2 | 0 | 1 | 1 | |||
Histologic grade | Grade 1 | 4 | 31 | 0.074 | 3 | 32 | 0.058 |
Grade 2 | 20 | 42 | 18 | 44 | |||
Grade 3 | 7 | 19 | 5 | 21 | |||
Tumor size | <10 cm | 17 | 44 | 0.539 | 13 | 48 | 0.569 |
≥10 cm | 14 | 48 | 13 | 49 | |||
Mitotic count | <10/10HPFs | 10 | 40 | 0.415 | 9 | 41 | 0.707 |
10 ≤ but < 20/10HPFs | 14 | 30 | 11 | 33 | |||
≥20/10HPFs | 7 | 22 | 6 | 23 | |||
FIGO stage | I/II | 10 | 52 | 0.023 | 8 | 54 | 0.028 |
III/IV | 21 | 40 | 18 | 43 | |||
Disease recurrence | No | 13 | 49 | 0.305 | 11 | 51 | 0.384 |
Yes | 18 | 43 | 15 | 46 |