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Table 2 Comparison of outcomes for patients with FDG-PET-positive and FDG-PET- negative recurrent papillary thyroid cancer

From: Fluorodeoxyglucose-positron emission tomography scan-positive recurrent papillary thyroid cancer and the prognosis and implications for surgical management

Characteristic

FDG-PET-positive n = 22

FDG-PET-negative n = 17

P value

Disease-free survival, (months), median (range)

15 (5–33)

41 (4–67)

n.s.

Surgical treatment, (n)

7

7

n.s.

131I uptake (yes/no), n (%)

5 (23%)

8 (47%)

n.s.

131I uptake in PET-positive lesion, n =

 

7

 

131I uptake elsewhere, n =

 

1

 

131I therapy (yes/no), n (%)

10 (46%)

6 (41%)

n.s.

Outcome, n (%)

  

n.s.

Stable disease

5 (24%)

5 (31%)

 

Loco-regional control without evidence of residual disease

2 (10%)*

2 (13%)

 

Progressive disease

9 (43%)

9 (56%)

 

Death†

5 (18%)†

0 (0%)†

 

Unknown

1

  
  1. *One of the two patients had no evidence of recurrent disease, although the Tg level was 3.8 ng/l. †There was a significant difference for ‘death’ between the PET + and PET– group (P = 0.04). 131I, whole-body radioactive iodine scan; FDG-PET, fluorodeoxyglucose-positron emission tomography; n.s., not significant.