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Table 1 HtrA1 mRNA expression in esophageal cancer tissue and its relationship with clinicopathological factors

From: HtrA1 expression associated with the occurrence and development of esophageal cancer

Pathologic parameter Cases HtrA1-positive rate (%) χ 2 P
Normal tissue 63 43 (68.25) 8.2286 0.004*
Carcinoma tissue 63 27 (42.86)
Sex     
 Male 50 23 (46.00) 0.9773 0.323
 Female 13 4 (30.77)
Age     
 < 60 19 6 (31.58) 1.4130 0.235
 ≥ 60 44 21 (47.73)   
Size of primary carcinoma (cm)     
 < 3 36 15 (41.67) 0.0486 0.825
 ≥ 3 27 12 (44.44)
Degree of differentiation     
 Well and moderately  differentiated 34 19 (55.88) 5.1169 0.024*
 Poorly differentiated 29 8 (27.59)
Pathological stage     
 I − II 33 19 (57.58) 6.1303 0.013*
 III − IV 30 8 (26.67)   
Lymph nodes metastasis     
 Negative 26 17 (65.38) 9.1739 0.002*
 Positive 37 10 (27.03)   
Distant metastasis     
 Negative 31 21 (67.74) 15.4325 0.000*
 Positive 32 6 (18.75)