Table 1 HtrA1 mRNA expression in esophageal cancer tissue and its relationship with clinicopathological factors
From: HtrA1 expression associated with the occurrence and development of esophageal cancer
Pathologic parameter | Cases | HtrA1-positive rate (%) | χ 2 | P |
|---|---|---|---|---|
Normal tissue | 63 | 43 (68.25) | 8.2286 | 0.004* |
Carcinoma tissue | 63 | 27 (42.86) | ||
Sex | ||||
Male | 50 | 23 (46.00) | 0.9773 | 0.323 |
Female | 13 | 4 (30.77) | ||
Age | ||||
< 60 | 19 | 6 (31.58) | 1.4130 | 0.235 |
≥ 60 | 44 | 21 (47.73) | ||
Size of primary carcinoma (cm) | ||||
< 3 | 36 | 15 (41.67) | 0.0486 | 0.825 |
≥ 3 | 27 | 12 (44.44) | ||
Degree of differentiation | ||||
Well and moderately differentiated | 34 | 19 (55.88) | 5.1169 | 0.024* |
Poorly differentiated | 29 | 8 (27.59) | ||
Pathological stage | ||||
I − II | 33 | 19 (57.58) | 6.1303 | 0.013* |
III − IV | 30 | 8 (26.67) | ||
Lymph nodes metastasis | ||||
Negative | 26 | 17 (65.38) | 9.1739 | 0.002* |
Positive | 37 | 10 (27.03) | ||
Distant metastasis | ||||
Negative | 31 | 21 (67.74) | 15.4325 | 0.000* |
Positive | 32 | 6 (18.75) |