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Table 4 Randomized controlled trials of adjuvant radiotherapy versus surgery alone for esophageal squamous cell carcinoma

From: Neoadjuvant versus adjuvant treatment: which one is better for resectable esophageal squamous cell carcinoma?

Studies Histology SCC (%) Treatment n MS (months) 5-year OS (%) P value
Kunath and Fischer [39] SCC 100 ART 50 to 55 Gy 23 9   NS
    Surgery 21 6   
Ténière and colleagues [40] SCC 100 ART 45 to 55 Gy 102 18 19 NS
    Surgery 119 18 19  
Fok and colleagues [41] SCC 100 ART 43 to 53 Gy 42 11 10 NS
    Surgery 39 22 16  
Zieren and colleagues [42] SCC 100 ART 56 Gy 33   23a NS
    Surgery 35   22a  
Xiao and colleagues [43] SCC 100 ART 50 to 60 Gy 220   41 NS
    Surgery 275   32  
  1. aThree-year overall survival (OS). ART adjuvant radiotherapy, MS median survival, NS, not significant, SCC squamous cell carcinoma.