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Table 2 Molecular factors involved in progression in PanCa cells related to diabetes

From: The bidirectional interation between pancreatic cancer and diabetes

Molecules Expression levels Role in PanCa Refs
IGF-1 and receptor Increased Increase the risk and worse survival [35, 36]
14-amino-acid peptide from S100A8 Increased Promote the growth of PanCa by activating Akt and NF-κB signaling [38, 39]
Regenerating gene I alpha protein Increased Accelerated cell proliferation [40]
  Increased Predictors of poor survival [41]
  Increased Contribute to determining diabetes [42]
  1. IGF-1, insulin-like growth factor 1; PanCa, pancreatic cancer.