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Table 2 Raw data and methodological quality of included trials

From: Systematic review and meta-analysis of Endostar (rh-endostatin) combined with chemotherapy versus chemotherapy alone for treating advanced non-small cell lung cancer

Studies Region Sequence generation Allocation concealment Blind Outcome data Selective outcome reporting Other sources of bias ITT Risk of bias
Wang JW 2005[11] Multi-center Random number table (SAS) Insufficient Clear No No Unclear Yes Low risk of bias
Yang L 2005[12] Multi-center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Cai L 2007[13] Single center Random number table (SPSS) Unclear Clear Yes No Unclear No Low risk of bias
Mu HY 2009[14] Single center Random number table (SPSS) Unclear Clear Yes No Unclear No Low risk of bias
Liao HY 2009[15] Single center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Zhang T 2009[16] Single center Random number table (SPSS) Unclear Clear Yes No Unclear No Low risk of bias
Liu J 2009[17] Single center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Ma JB 2009[18] Single center Random number table (SPSS) Unclear Unclear Yes Yes Unclear No Unclear risk of bias
Shi GY 2009[19] Multi-center Random number table (SAS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Han BH 2011[20] Multi-center Random number table (SPSS) Insufficient Clear Yes No Unclear No Low risk of bias
Zhao X 2011[21] Single center Random number table (SPSS) Unclear Clear Yes No Unclear No Low risk of bias
Hu HT 2011[22] Single center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Wen F 2011[23] Single center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
Zhang H 2011[24] Multi-center unclear Unclear Unclear Yes No Unclear No Unclear risk of bias
Chen Q 2011[25] Single center Random number table (SPSS) Unclear Unclear Yes No Unclear No Unclear risk of bias
  1. ITT, intention-to-treat; SAS, SAS software; SPSS, SPSS software.