Figure 2From: Up-regulated oncoprotein P28GANK correlates with proliferation and poor prognosis of human gliomaInhibition of p28GANK expression represses the proliferation of U251 cell in vitro and in vivo. (A) The expression of p28GANK in Si-U251 cells was markedly lower compared with the controls (Con-251 and U251) on Western blot analysis. (B): Growth curves of U251, Con-U251 and Si-U251 cells by MTT assays. The results presented were the mean of three replicates. (C) Comparison of glioma cell tumorigenicity in mice. The left flank was injected with Si-U251 cells, and the right flank was injected with Con-U251 cells. (D) Tumor volumes formed by si-U251 were significantly smaller than Con-U251 cells. P < 0.05.Back to article page