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Table 3 Relationship between TCT diagnosis and hTERC amplification in exfoliated cervical epithelial cells

From: The detection of hTERC amplification using fluorescence in situ hybridization in the diagnosis and prognosis of cervical intraepithelial neoplasia: a case control study

TCT Diagnosis Number Percentage of positive cells (mean ± SD) Incidence of positive cases (%)
Control group 40 2.4 ± 1.2 0 (0.0)
Study group 151   
NILM 16 3.2 ± 2.1 0 (0.0)
ASCUS 29 8.7 ± 6.3* 13 (44.8)*
LSIL 34 10.8 ± 4.8* 23 (67.6)*
HSIL 44 23.9 ± 15.0* 41 (93.2)*
SCC 28 31.07 ± 22.0* 28 (100)*
  1. TCT, thinprep cytologic test; FISH, fluorescence in situ hybridization; hTER C, human telomerase mRNA component gene; Number, number of cases; NILM, negative for intraepithelial lesion or malignancy; ASCUS, atypical squamous cells of undetermined significance; LSIL, low-grade squamous intraepithelial lesion; HSIL, high-grade squamous intraepithelial lesion; SCC, squamous cell carcinoma. *P < 0.05(compared to the control group).