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Table 2 hTERC amplification measured by FISH in exfoliated cervical epithelial cells

From: The detection of hTERC amplification using fluorescence in situ hybridization in the diagnosis and prognosis of cervical intraepithelial neoplasia: a case control study

Diagnosis Number Percentage of positive cell (mean ± SD) Incidence of positive cases (number positive/total number)
Control group 40 2.4 ± 1.2 0 (0.0)
Study group 151   
CIN I 27 9.2 ± 4.6* 44.4% (12 /27)*
CIN II/III 54 16.0 ± 14.4* 85.1% (46/54)*
Carcinoma in situ 17 19.7 ± 13.3* 88.3% (15 /17)*
Invasive Carcinoma 28 47.0 ± 25.2 * 100% (28 /28)*
CIN LEEP post-treatment 11 7.2 ± 2.7* 18.2% (2 /11)
Cervical cancer post-treatment 14 7.1 ± 2.0* 14.3% (2 /14)
  1. FISH, fluorescence in situ hybridization; hTERC, human telomerase mRNA component gene; Number, number of cases; CIN, cervical intraepithelial neoplasia; LEEP, loop electrical excision procedure. *P < 0.05 (compared with the control group).