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Figure 1 | World Journal of Surgical Oncology

Figure 1

From: The detection of hTERC amplification using fluorescence in situ hybridization in the diagnosis and prognosis of cervical intraepithelial neoplasia: a case control study

Figure 1

Photographs of hTERC amplification using FISH in the normal cervix, CIN I, CIN III and cervical carcinoma. (A) Normal cervix. Among the normal cervical epithelial cells, there were two red and two green signals in nuclei during cell interphase. (B) CIN I. The hTERC amplification in heterogeneous cells was demonstrated as more than two red signals and no less than two green signals in the nucleus during cell interphase. The hTERC amplification test showed that the percentage of cells with more than two red signals was on average 9.2%. (C) CIN III. The hTERC amplification test showed that the percentage of cells with more than two red signals was on average 16.0%. (D) Cervical cacinoma. The hTERC amplification test showed that the percentage of cells with more than two red signals was on average 47.0%. hTERC, human telomerase mRNA component gene; FISH, fluorescence in situ hybridization; CIN, cervical intraepithelial neoplasia.

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