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Table 4 Cox regression analysis of the independent factors affecting overall survival and disease-free survival in primary breast carcinoma

From: Peritumoral lymphangiogenesis induced by vascular endothelial growth factor C and D promotes lymph node metastasis in breast cancer patients

 

Overall survival

Disease-free survival

OR (95% CI)

P-value

OR (95% CI)

P-value

P-LVD

3.077 (2.086-4.539)

0.000

2.245 (1.602-3.144)

0.001

I-LVD

0.927 (0.709-1.212)

0.579

1.086 (0.830-1.422)

0.547

VEGF-C

0.637 (0.225-1.804)

0.396

0.432 (0.169-1.103)

0.079

VEGF-D

1.900 (0.690-5.230)

0.214

2.025 (0.842-4.872)

0.115

LNM

3.564 (1.081-11.749)

0.037

13.333 (1.125-68.667)

0.040

LVI

1.218 (0.457-3.250)

0.693

1.421 (0.566-3.567)

0.454

TNM stage

4.464 (1.111-18.182)

0.035

5.917 (1.681-20.833)

0.006

  1. I-LVD, intratumoral lymphatic vessel density; LNM, lymph node metastasis; LVI, lymphatic vessel invasion; P-LVD, peritumoral lymphatic vessel density; TNM, tumor,node,metastasis stage.