Table 3 Univariate analysis of the clinicopathologic factors associated with right upper paraesophageal lymphnode metastasis
Status of right upper paraesophageal lymph node | p-Value | |||
|---|---|---|---|---|
Metastasis(−)n = 229 | Metastasis(+)n = 14 | |||
Age(yrs) | Mean(95%CIa) | 49.51(48.04-50.97) | 50.07(41.11-59.03) | 0.73 |
Gender | Male | 38 | 5 | 0.07 |
Female | 191 | 9 | ||
Tumor size | Mean(95%CIa) | 1.0195(0.9455-1.0938) | 1.6429(1.1599-2.1258) | 0.006 |
<1 cm | 125 | 3 | 0.016 | |
≥1 cm | 124 | 11 | ||
Tumor location | Left | 77 | 1 | 0.06 |
Right | 95 | 6 | ||
Isthmus | 6 | 0 | ||
Both | 51 | 7 | ||
Solitary lesion | Upper | 34 | 3 | 0.15 |
Middle | 80 | 1 | ||
Lower | 41 | 2 | ||
Isthmus | 6 | 0 | ||
Multifocal lesion | Both lobes | 13 | 1 | |
Affected lobe | 51 | 7 | ||
Extrathyroidal extension | (−) | 100 | 1 | 0.009 |
(+) | 129 | 13 | ||
Lymphatic invasion | (−) | 119 | 0 | 0.000 |
(+) | 110 | 14 | ||
Multiplicity | (−) | 156 | 4 | 0.002 |
(+) | 73 | 10 | ||
Vascular invasion | (−) | 219 | 13 | 0.49 |
(+) | 10 | 1 | ||
Combined thyroiditis | (−) | 185 | 13 | 0.39 |
Hashimoto thyroiditis | 27 | 0 | ||
Lymphocytic thyroiditis | 17 | 1 | ||
Retrieved central lymph nodes | Mean(95%CIa) | 8.2664(7.5873-8.9454) | 9.2143(6.0666-12.3619) | 0.33 |
Metastatic central lymph nodes | Mean(95%CIa) | 1.3493(1.0205-1.6782) | 4.9286(2.5700-7.2872) | 0.004 |
Retrieved lateral lymph nodes | Mean(95%CIa) | 20.08(17.0944-23.0656) | 18.6(13.2234-23.9766) | 0.64 |
Metastatic lateral lymph nodes | Mean(95%CIa) | 0.2882(0.1709-0.4055) | 3.5(1.4029-5.5971) | 0.000 |