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Table 3 Univariate analysis of the clinicopathologic factors associated with right upper paraesophageal lymphnode metastasis

From: Clinical predictors of right upper paraesophageal lymph node metastasis from papillary thyroid carcinoma

   Status of right upper paraesophageal lymph node p-Value
   Metastasis(−)n = 229 Metastasis(+)n = 14  
Age(yrs) Mean(95%CIa) 49.51(48.04-50.97) 50.07(41.11-59.03) 0.73
Gender Male 38 5 0.07
  Female 191 9  
Tumor size Mean(95%CIa) 1.0195(0.9455-1.0938) 1.6429(1.1599-2.1258) 0.006
  <1 cm 125 3 0.016
  ≥1 cm 124 11  
Tumor location Left 77 1 0.06
  Right 95 6  
  Isthmus 6 0  
  Both 51 7  
Solitary lesion Upper 34 3 0.15
  Middle 80 1  
  Lower 41 2  
  Isthmus 6 0  
Multifocal lesion Both lobes 13 1  
  Affected lobe 51 7  
Extrathyroidal extension (−) 100 1 0.009
  (+) 129 13  
Lymphatic invasion (−) 119 0 0.000
  (+) 110 14  
Multiplicity (−) 156 4 0.002
  (+) 73 10  
Vascular invasion (−) 219 13 0.49
  (+) 10 1  
Combined thyroiditis (−) 185 13 0.39
  Hashimoto thyroiditis 27 0  
  Lymphocytic thyroiditis 17 1  
Retrieved central lymph nodes Mean(95%CIa) 8.2664(7.5873-8.9454) 9.2143(6.0666-12.3619) 0.33
Metastatic central lymph nodes Mean(95%CIa) 1.3493(1.0205-1.6782) 4.9286(2.5700-7.2872) 0.004
Retrieved lateral lymph nodes Mean(95%CIa) 20.08(17.0944-23.0656) 18.6(13.2234-23.9766) 0.64
Metastatic lateral lymph nodes Mean(95%CIa) 0.2882(0.1709-0.4055) 3.5(1.4029-5.5971) 0.000
  1. aCI: confidence interval.