Skip to main content

Table 1 Quality and characteristics of included studies

From: Meta-analysis of surgical resection and radiofrequency ablation for early hepatocellular carcinoma

Reference Date Design Jadad score Treatment Number of patients Sex (M/F) Mean age (years) Tumor number (single/multiple) Mean tumor size (cm)
Nishikawa 2011 NRCT 1 SR 69 50/19 67.4 ± 9.7 69/0 2.68 ± 0.49
     RFA 162 95/67 68.4 ± 8.7 162/0 1.99 ± 0.62
Tashiro 2011 NRCT 1 SR 199 137/62 65.7 ± 9.0 132/67 2.1 ± 0.63
     RFA 87 53/34 66.3 ± 8.2 67/20 1.8 ± 0.52
HUNG 2011 NRCT 1 SR 229 184/45 60.07 ± 12.56 181/48 2.88 ± 1.06
     RFA 190 121/69 67.42 ± 11.45 152/38 2.37 ± 0.92
Nanashima 2010 NRCT 1 SR 144 112/32 63.6 ± 8.8 128/16 NA
     RFA 56 36/20 67.7 ± 8.5 51/5 NA
Huang 2010 RCT 4 SR 115 85/30 55.91 ± 12.68 89/26 NA
     RFA 115 79/36 56.57 ± 14.30 84/31 NA
Ueno 2009 NRCT 1 SR 123 82/41 67 (28 to 85) 110/13 2.7 ± 0.1
     RFA 155 100/55 66 (40 to 79) 101/54 2.0 ± 0.1
Guglielmi 2008 NRCT 1 SR 91 73/18 NA 69/22 NA
     RFA 109 88/21 NA 65/44 NA
Hiraoka 2008 NRCT 1 SR 59 44/15 62.4 ± 10.6 NA 22.7 ± 5.5
     RFA 105 76/29 69.4 ± 9.1 NA 19.8 ± 5.2
Abu-Hilal 2008 NRCT 3 SR 34 26/8 67 NA 3.8 (1.3 to 5)
     RFA 34 27/7 65 NA 3 (2 to 5)
Takahashi 2007 NRCT 1 SR 53 39/14 66 (41 to 80) 41/12 2.5 (1 to 5)
     RFA 171 120/51 69 (44 to 84) 124/47 2.1 (0.7 to 4.8)
Chen 2006 RCT 4 SR 90 75/15 49.4 ± 10.9 NA NA
     RFA 71 56/15 51.9 ± 11.2 NA NA
Hong 2005 NRCT 1 SR 93 69/24 49.2 ± 9.9 NA 2.5 ± 0.8
     RFA 55 41/14 59.1 ± 9.6 NA 2.4 ± 0.6
Vivarell 2004 NRCT 2 SR 79 57/22 65.2 ± 8.2 66/13 NA
     RFA 79 67/12 67.8 ± 8.7 46/33 NA
  1. NA: Not available; NRCT: non-randomized controlled trial; RCT: randomized controlled trial; RFA: radiofrequency ablation; SR: surgical resection.