Skip to main content

Table 3 Coxā€™s proportional hazards regression models for the general population, ILC and IDC groups

From: Tumor characteristics and the clinical outcome of invasive lobular carcinoma compared to infiltrating ductal carcinoma in a Chinese population

Variables

RFS

OS

RR (95% CI)

P value

RR (95% CI)

P value

For general

Ā Ā Ā Ā 

ā€ƒHistological type

1.32 (0.82-2.12)

0.248

1.71 (0.91-3.21)

0.098

ā€ƒAge (years)ā€‰ā‰¤ā€‰50

1.23 (0.94-1.59)

0.131

1.43 (0.75-2.73)

0.284

ā€ƒTumor size (cm) >2

1.47 (0.90-2.31)

0.124

1.71 (0.73-4.00)

0.215

ā€ƒNodes positive

1.61 (1.37-1.88)

<0.001

1.40 (1.08-1.81)

0.012

ā€ƒHigher TNM stage

1.56 (1.01-2.24)

0.016

1.78 (1.03-3.07)

0.039

ā€ƒER positive

0.62 (0.43-0.91)

0.016

0.55 (0.31-1.00)

0.065

ā€ƒPR positive

0.59 (0.40-0.89)

0.011

0.51 (0.28-0.94)

0.031

ā€ƒHR positive

0.54 (0.32-0.91)

0.022

0.46 (0.21-1.02)

0.054

ā€ƒHER2/neu positive

1.21 (0.93-1.58)

0.157

1.24 (0.83-1.85)

0.304

ā€ƒChemotherapy

0.57 (0.32-1.03)

0.060

0.57 (0.24-1.35)

0.200

ā€ƒRadiotherapy

0.54 (0.40-0.75)

<0.001

1.21 (0.74-2.02)

0.414

ā€ƒHormonotherapy

0.68 (0.51-0.90)

0.008

0.73 (0.47-1.13)

0.159

For ILC

Ā Ā Ā Ā 

ā€ƒAge (years)ā€‰ā‰¤ā€‰50

5.72 (0.83-39.32)

0.076

0.92 (0.81-1.04)

0.182

ā€ƒTumor size (cm) >2

2.51 (0.61-10.41)

0.204

2.21 (0.97-5.01)

0.058

ā€ƒNodes positive

2.87 (1.06-7.69)

0.038

5.55 (0.93-33.33)

0.060

ā€ƒHigher TNM stage

4.79 (2.79-11.85)

0.002

3.31 (2.15-9.45)

0.006

ā€ƒER positive

1.04 (0.175-6.21)

0.964

1.98 (0.15-25.38)

0.600

ā€ƒPR positive

0.52 (0.10-2.58)

0.420

0.28 (0.02-3.24)

0.308

ā€ƒHR positive

0.66 (0.05-9.24)

0.760

0.39 (0.01-20.20)

0.643

ā€ƒHER2/neu positive

1.45 (0.41-5.18)

0.569

0.85 (0.21-3.42)

0.822

ā€ƒChemotherapy

0.29 (0.02-4.73)

0.383

0.32 (0.12-1.05)

0.060

ā€ƒRadiotherapy

0.86 (0.27-2.78)

0.809

1.22 (0.26-5.72)

0.796

ā€ƒHormonotherapy

1.38 (0.42-4.54)

0.595

0.90 (0.21-3.76)

0.889

For IDC

Ā Ā Ā Ā 

ā€ƒAge (years)ā€‰ā‰¤ā€‰50

1.21 (0.92-1.59)

0.186

1.55 (1.00-2.34)

0.049

ā€ƒTumor size (cm) >2

1.39 (0.84-2.32)

0.201

2.34 (0.84-6.55)

0.105

ā€ƒNodes positive

1.62 (1.37-1.91)

<0.001

1.66 (1.27-2.17)

<0.001

ā€ƒHigher TNM stage

1.52 (1.03-2.23)

0.056

1.93 (1.07-3.48)

0.029

ā€ƒER positive

0.62 (0.42-0.93)

0.021

0.51 (0.27-0.97)

0.040

ā€ƒPR positive

0.60 (0.39-0.91)

0.016

0.47 (0.25-0.91)

0.025

ā€ƒHR positive

0.53 (0.31-0.92)

0.023

0.38 (0.16-0.88)

0.025

ā€ƒHER2/neu positive

1.19 (0.91-1.57)

0.206

1.26 (0.82-1.94)

0.292

ā€ƒChemotherapy

0.60 (0.33-1.10)

0.099

0.82 (0.33-2.03)

0.662

ā€ƒRadiotherapy

0.51 (0.38-0.69)

<0.001

0.47 (0.30-0.75)

0.002

ā€ƒHormonotherapy

0.64 (0.47-0.86)

0.004

0.67 (0.42-1.08)

0.101

  1. HR, hormone receptor; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; OS, overall survival; RFS, relapse/metastasis free survival.