From: Primary malignant non-Hodgkin’s lymphoma of the breast: a study of seven cases and literature review
Authors | Type of study | Number of patients | Histology | Treatment | Follow-up (years) | Survival |
---|---|---|---|---|---|---|
Jennings et al. 2007 | Database analysis | 465 | DLBCL, follicular lymphoma, MALT | Mastectomy +/− Chemotherapy +/− Radiotherapy | 4 | DFS 44.5% overall, no benefit from mastectomy |
Ryan et al., 2008 | Retrospective | 204 | DLBCL, MALT | Surgery, chemotherapy, radiotherapy, combined therapy | 5.5 | Median OS: 8 years, Median PFS: 5.5 |
Aviles et al., 2005 | Prospective | 96 | DLBCL | RT (45 Gy) | 10 | CR: 66%, EFS: 50%, OS: 50% |
CHOP-21 × 6 | CR: 59%, EFS: 57%, OS: 50% | |||||
CHOP × 6/RT | CR: 88%, EFS: 83%, OS: 76% | |||||
Aviles et al., 2007 | Prospective Single arm | 32 | DLBCL | CEOP-R 14 × 6 | 5.3 | CR: 87%, EFS: 63% |
Jeanneret- Sozzi et al., 2008 | Meta- analysis | 84 | High-, intermediate-, low-grade lymphomas | Surgery +/− Radiotherapy +/− Chemotherapy | 4 | OS 5 years 53%, DFS 41% local control rate 87% |