Table 4 Relation among membrane-bound ERα (mERα) expression, EGFR mutation and clinicopathological characteristics
Characteristics | mERα negative & EGFR wild | mERα positive or EGFR mutant | mERα positive & EGFR mutant | p-value |
|---|---|---|---|---|
Patients, number | 16 | 20 | 15 | |
Age (mean), year | 67.9 | 63.7 | 69.7 | 0.097 |
Sex | ||||
Male | 23 | 8 | 15 | 0.036 |
Female | 28 | 18 | 10 | |
PET SUVmax | 5.03 | 5.34 | 7.77 | 0.168 |
Tumor differentiation | 0.150 | |||
well | 11 | 17 | 7 | |
moderate+poor | 5 | 3 | 8 | |
Vascular invasion | <0.001 | |||
negative | 15 | 16 | 4 | |
positive | 1 | 4 | 11 | |
VEGF expression | 0.018 | |||
negative | 10 | 7 | 2 | |
positive | 6 | 13 | 13 | |
Ki-67 expression | 0.003 | |||
negative | 11 | 15 | 3 | |
positive | 5 | 5 | 12 |