Long-term survival from adenocarcinoma of the esophagus after transthoracic and transhiatal esophagectomy

Table 5 Survival rates according to operative procedure, lymph node metastases and primary tumor infiltration in patients treated for adenocarcinoma of the esophagus

	N	Observed deaths	S_O(5)	95% CI	S_O(10)	95% CI	SMR	95% CI	RMR	95% CI	P value
Total	88	72	25.0	16.2–34.4	20.8	11.8–29.9	6.3	5.0–8.0
Transthoracic	33	26	31.2	15.5–46.8	27.8	10.4–43.2	6.2	4.2–9.1	1	ref	ref
Transhiatal	55	46	21.3	11.5–32.7	16.6	7.2–27.6	6.4	4.8–8.5	1.14	0.67–1.96	0.63
pN0	34	20	52.6	34.0–67.5	48.9	27.2–64.2	2.8	1.8–4.3	1	ref	ref
pN1	54	52	7.5	2.2–15.9	3.8	0.5–10.0	12.3	9.4–16.2	2.22	1.24–3.98	0.007
pT1	13	5	68.4	35.6–86.2	57.0	14.9–78.9	1.7	0.7–4.1	1	ref	ref
pT2	22	18	38.1	18.0–57.0	33.3	11.8–52.2	3.8	2.4–6.0	1.47	0.49–4.48	0.50
pT3	53	49	9.4	2.9–18.5	7.1	1.9–15.5	13.4	10.1–17.7	3.22	1.16–8.91	0.024
Male	75	62	24.1	15.0–34.2	19.2	10.1–28.9	6.7	5.2–8.6	1	ref	ref
Female	13	10	30.8	6.8–53.7	30.8	3.9–53.7	4.7	2.5–8.7	1.84	0.88–3.86	0.11
<60	28	23	25.0	9.9–41.0	20.8	6.7–36.5	7.9	5.3–11.9
60–69	23	17	27.3	10.8–45.4	27.3	6.2–45.4	2.4	1.5–3.9
70–79	28	23	32.1	15.1–48.7	21.4	7.3–38.3	1.5	0.98–2.2
80+	9	9	0	–	0	–	1.3	0.7–2.4
Age/10 years									0.43	0.35–0.52	<0.001

S_O(5) and S_O(10) are the observed survivals in percent (Kaplan–Meier) at 5 and 10 years respectively with 95% CI. The SMR is the observed mortality (Obs) divided by the mortality in the general population with the same composition of age, gender, and year of birth (Expected number of deaths, Exp) as that of the study group. The RMRs compare the SMRs for different levels of the variables RMR_Gender = SMR_Female/SMR_Male , but adjusted for the other factors in the table.

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