Variables
| |
HR (95% CI)
|
P-value
|
---|
Gender
| | |
0.020
|
|
Female
|
1.0
| |
|
Male
|
1.278 (1.040, 1.572)
| |
Age, years
| | |
0.007
|
|
< 65
|
1.0
| |
| ≧ 65 |
1.317 (1.078, 1.608)
| |
Location
| | |
0.020
|
|
Colon
|
1.0
| |
|
Rectum
|
1.267 (1.038, 1.547)
| |
Size, cm
| | |
0.112
|
|
< 5
|
1.0
| |
| ≧ 5 |
1.184 (0.961, 1.459)
| |
Preoperative serum CEA, ng/ml
| |
< 0.001
|
|
< 5.0
|
1.0
| |
| ≧ 5.0 |
1.483 (1.203, 1.828)
| |
Depth of invasiona
| |
< 0.001
|
|
T1, T2
|
1.0
| |
|
T3, T4
|
2.253 (1.534, 3.308)
| |
Lymph node metastasisa
| |
< 0.001
|
|
N0
|
1.0
| |
|
N1, N2
|
2.427 (1.893, 3.105)
| |
Distant metastasisa
| |
< 0.001
|
|
M0
|
1.0
| |
|
M1
|
4.165 (3.350, 5.179)
| |
Operating facility
| |
0.032
|
|
Center A
|
1.0
| |
|
Center B
|
1.192 (1.002, 1.395)
| |
Histological type
| |
< 0.001
|
|
NMA
|
1.0
| |
|
MA
|
2.226 (1.618, 3.062)
| |
- aStaging of tumor (T), nodes (N), and metastases (M) [24]; HR, hazard ratio; CI, confidence interval; NMA, non-mucinous adenocarcinoma; MA, mucinous adenocarcinoma.