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Table 4 Multivariate Cox proportional hazards analysis of overall survival in colorectal adenocarcinoma

From: The clinicopathological features of colorectal mucinous adenocarcinoma and a therapeutic strategy for the disease

Variables

 

HR (95% CI)

P-value

Gender

  

0.020

 

Female

1.0

 
 

Male

1.278 (1.040, 1.572)

 

Age, years

  

0.007

 

< 65

1.0

 
 

≧ 65

1.317 (1.078, 1.608)

 

Location

  

0.020

 

Colon

1.0

 
 

Rectum

1.267 (1.038, 1.547)

 

Size, cm

  

0.112

 

< 5

1.0

 
 

≧ 5

1.184 (0.961, 1.459)

 

Preoperative serum CEA, ng/ml

 

< 0.001

 

< 5.0

1.0

 
 

≧ 5.0

1.483 (1.203, 1.828)

 

Depth of invasiona

 

< 0.001

 

T1, T2

1.0

 
 

T3, T4

2.253 (1.534, 3.308)

 

Lymph node metastasisa

 

< 0.001

 

N0

1.0

 
 

N1, N2

2.427 (1.893, 3.105)

 

Distant metastasisa

 

< 0.001

 

M0

1.0

 
 

M1

4.165 (3.350, 5.179)

 

Operating facility

 

0.032

 

Center A

1.0

 
 

Center B

1.192 (1.002, 1.395)

 

Histological type

 

< 0.001

 

NMA

1.0

 
 

MA

2.226 (1.618, 3.062)

 
  1. aStaging of tumor (T), nodes (N), and metastases (M) [24]; HR, hazard ratio; CI, confidence interval; NMA, non-mucinous adenocarcinoma; MA, mucinous adenocarcinoma.