Variables
| |
HR (95% CI)
|
P-value
|
---|
Gender
| | |
0.004
|
|
Female
|
1.0
| |
|
Male
|
1.349 (1.098, 1.656)
| |
Age, years
| | |
0.049
|
|
< 65
|
1.0
| |
| ≧ 65 |
1.217 (1.001, 1.480)
| |
Location
| | |
0.049
|
|
Colon
|
1.0
| |
|
Rectum
|
1.212 (1.000, 1.468)
| |
Size, cm
| | |
< 0.001
|
|
< 5
|
1.0
| |
| ≧ 5m |
2.432 (2.001, 2.955)
| |
Preoperative serum CEA, ng/ml
| |
< 0.001
|
|
< 5.0
|
1.0
| |
| ≧ 5.0 |
3.223 (2.654, 3.915)
| |
Depth of invasiona
| |
< 0.001
|
|
T1, T2
|
1.0
| |
|
T3, T4
|
6.122 (4.311, 8.694)
| |
Lymph node metastasisa
| |
< 0.001
|
|
N0
|
1.0
| |
|
N1, N2
|
4.527 (3.972, 5.122)
| |
Distant metastasisa
| |
< 0.001
|
|
M0
|
1.0
| |
|
M1
|
8.133 (6.697, 9.877)
| |
Operating facility
| |
< 0.001
|
|
Center A
|
1.0
| |
|
Center B
|
2.365 (1.943, 2.878)
| |
Histological type
| |
< 0.001
|
|
NMA
|
1.0
| |
|
MA
|
2.614 (1.905, 3.585)
| |
- aStaging of tumor (T), nodes (N), and metastases (M) [24]; HR, hazard ratio; CI, confidence interval; NMA, non-mucinous adenocarcinoma; MA, mucinous adenocarcinoma.