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Table 6 The effects of BRAF V600E mutation on progression in multiple PTC patients

From: BRAFV600E status and clinical characteristics in solitary and multiple papillary thyroid carcinoma: experience of 512 cases at a clinical center in China

BRAFv600E mutation All negative All positive Mixed P value
Number 61 40 35  
Age ≤ 14 15 (24.6%) 1 (2.5%) 1 (2.9%) 0.001
Tall cell variant 3 (4.9%) 8 (20.0%) 6 (17.1%) 0.597
Extrathyroidal invasion 10 (16.4%) 17 (42.5%) 8 (22.9%) 0.214
Vascular invasion 3 (4.9%) 8 (20.0%) 4 (11.4%) 0.097
Hashimoto’s thyroiditis 12 (19.7%) 14 (35.0%) 10 (28.6%) 0.088
Lymph node metastasis 27 (44.3%) 32 (80.0%) 15 (42.9%) < 0.001
Distant metastasis 1 (1.6%) 3 (7.5%) 2 (5.7%) 0.065
10-year survival rate 56 (91.8%) 35 (87.5%) 34 (97.1%) 0.336