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Table 4 BRAF V600E mutational status in 512 patients of PTC

From: BRAFV600E status and clinical characteristics in solitary and multiple papillary thyroid carcinoma: experience of 512 cases at a clinical center in China

Characteristic BRAFV600E mutation P value
Positive Negative
Number 263 249  
Age (yr) 45.4 ± 12.3 40.8 ± 16.2 0.028
Male/ Female ratio 79/184 48/201 0.003
Extrathyroidal invasion 91 (34.6%) 37 (14.9%) < 0.001
Multiple PTC 75 (28.5%) 61 (24.5%) 0.184
Central LNM* 151 (57.4%) 56 (22.5%) < 0.001
Lateral LNM* 83 (31.6%) 31 (12.5%) < 0.001
Distant metastasis 18 (6.8%) 12 (4.8%) 0.261
  1. LNM: lymph node metastases.