Figure 1
Endometrial pathology and survivin, ER, and PR expression before and 6 to 7 months after REA treatment in DUB patients with complex endometrial hyperplasia. (A) Before REA, the endometrium showed complex hyperplasia, ‘back to back’ glandular hyperplasia, leather bag shape glandular enlargement. (B) Six to seven months after REA, glandular tissue became fibrous tissue with scarce glands and blood vessels in endometrial curettage. (C) Before REA, the expression of survivin (strong positive). (D) Six months after REA, the expression of surviving showed weak positive. (E) Before REA, the expression of ER (strong positive). (F) Six months after REA, the expression of ER showed weak positive. (G) Before REA, the expression of PR (strong positive). (H) Six months after REA, the expression of PR showed weak positive. DUB, dysfunctional uterine bleeding; ER, Estrogen receptors; PR, Progesterone receptor; REA, Radiofrequency endometrial ablation.