Variables | Recurrence-free survival | Overall survival | ||||
---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||
p | HR (95%CI) | p | p | HR (95%CI) | p | |
IMA ≤ 2 cm | ||||||
Age (> 65 vs. ≤ 65) | 0.564 | 0.304 | ||||
Gender (male vs. female) | 0.181 | 0.689 | ||||
Smoking (current or ex vs. non-smoker) | 0.456 | 0.286 | ||||
Cardiovascular disease (present vs. absent) | 0.444 | 0.278 | ||||
Diabetes mellitus (present vs. absent) | 0.177 | 0.649 | ||||
%predicted FEV1 (> 80% vs. ≤ 80%) | 0.475 | 0.695 | ||||
CEA (> 5 ng/ml vs. ≤ 5 ng/ml) | 0.141 | 0.511 | ||||
VPI (present vs. absent) | 0.468 | 0.714 | ||||
Tumor location (upper and middle vs. lower) | 0.465 | 0.741 | ||||
Surgical procedure (limited resection vs. lobectomy) | 0.953 | 0.552 | ||||
Lymph node status (positive vs. negative) | < 0.001 | 6.981 (2.433–20.034) | < 0.001 | 0.017 | 4.296 (1.291–14.297) | 0.020 |
IMA > 2.1 to 3 cm | ||||||
Age (> 65 vs. ≤ 65) | 0.767 | 0.880 | ||||
Gender (male vs. female) | 0.648 | 0.137 | ||||
Smoking (current or ex vs. non-smoker) | 0.887 | 0.330 | ||||
Cardiovascular disease (present vs. absent) | 0.422 | 0.417 | ||||
Diabetes mellitus (present vs. absent) | 0.971 | 0.857 | ||||
%predicted FEV1 (> 80% vs. ≤ 80%) | 0.906 | 0.352 | ||||
CEA (> 5 ng/ml vs. ≤ 5 ng/ml) | 0.263 | 0.253 | ||||
VPI (present vs. absent) | 0.845 | 0.777 | ||||
Tumor location (upper and middle vs. lower) | 0.664 | 0.881 | ||||
Surgical procedure (limited resection vs. lobectomy) | 0.010 | 2.417 (1.157–5.049) | 0.019 | 0.122 | ||
Lymph node status (positive vs. negative) | 0.002 | 3.444 (1.492–7.949) | 0.004 | 0.005 | 4.059 (1.495–11.025) | 0.005 |