Variables | Recurrence-free survival | Overall survival | ||||
---|---|---|---|---|---|---|
Univariate | Multivariate | Univariate | Multivariate | |||
p | HR (95%CI) | p | p | HR (95%CI) | p | |
Age (> 65 vs. ≤ 65) | 0.597 | 0.663 | ||||
Gender (male vs. female) | 0.378 | 0.138 | ||||
Smoking (current or ex vs. non-smoker) | 0.404 | 0.756 | ||||
Tumor size (2.1–3 cm vs. ≤ 2 cm) | 0.008 | 1.286 (1.019–1.621) | 0.033 | 0.110 | ||
Cardiovascular disease (present vs. absent) | 0.397 | 0.211 | ||||
Diabetes mellitus (present vs. absent) | 0.149 | 0.622 | ||||
%predicted FEV1 (> 80% vs. ≤ 80%) | 0.885 | 0.267 | ||||
CEA (> 5 ng/ml vs. ≤ 5 ng/ml) | 0.091 | 1.344 (0.782–2.309) | 0.284 | 0.246 | ||
VPI (present vs. absent) | 0.319 | 0.622 | ||||
Tumor location (upper and middle vs. lower) | 0.378 | 0.870 | ||||
Surgical procedure (limited resection vs. lobectomy) | 0.170 | 0.239 | ||||
Lymph node status (positive vs. negative) | < 0.001 | 4.204 (2.126–8.315) | < 0.001 | < 0.001 | 4.497 (2.106–9.603) | < 0.001 |