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Table 6 Sub-group analysis of clinical characteristics

From: Clinical implications of pediatric biliary intraepithelial neoplasia diagnosed from a choledochal cyst specimen

That

Normal pathology

BilIN

p-value

(n = 314)

(n = 15)

Sex

  

0.342

Male

69 (22.0%)

5 (33.3%)

 

Female

245 (78.0%)

10 (66.7%)

 

Age at operation (months)

24.0 (4.2–54.0)

17.0 (6.0–47.0)

0.708

APBDU

 

0.680

No

38 (12.3%)

1 (6.7%)

Yes

182 (58.7%)

11 (73.3%)

Unknown

90 (29.0%)

3 (20.0%)

Preoperative lab findings

   

AST (IU/L)

34.0 [28.0;50.0]

38.0 [31.5;46.0]

0.465

ALT (IU/L)

20.0 [12.0;54.0]

17.0 [10.5;33.0]

0.550

T.bil (mg/dL)

0.6 [ 0.4; 2.5]

0.8 [ 0.5; 4.8]

0.285

D.bil (mg/dL)

0.3 [ 0.1; 0.8]

0.5 [ 0.3; 1.0]

0.149

Amylase (U/L)

66.0 [32.0;112.0]

121.5 [45.0;154.0]

0.108

Lipase (U/L)

36.5 [20.0;90.5]

110.0 [47.0;693.0]

0.034

Leukocytosis

 

0.580

No

229 (73.4%)

10 (66.7%)

Yes

83 (26.6%)

5 (33.3%)

  1. BilIN, biliary intraepithelial neoplasia; CC: choledochal cyst; APBDU, anomalous pancreaticobiliary ductal union; AST, aspartate transferase; ALT, alanine transaminase; T.bil, total bilirubin; D.bil, direct bilirubin. Bold indicates a significant p-value (p < 0.05)