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Fig. 2 | World Journal of Surgical Oncology

Fig. 2

From: Clinical implications of pediatric biliary intraepithelial neoplasia diagnosed from a choledochal cyst specimen

Fig. 2

Hematoxylin and eosin (H&E) and immunohistochemical staining. H&E staining and immunohistochemical staining for p53, Ki67, MUC1, and S100P in normal bile duct tissue and low- and high-grade biliary intraepithelial neoplasia (BilIN) arising from a choledochal cyst. BilINs exhibit increased expressions of p53, Ki67, and MUC1 compared to those in normal biliary epithelial tissue. High-grade BilIN displays higher levels of p53 and Ki67 expression than low-grade BilIN. S100P expression does not differ between cases.

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