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Table 2 Investigations ordered as staging for patients with R-NETs based on grade

From: Impact of grade on workup of rectal neuroendocrine tumors: a retrospective cohort study

Investigations

Grade 1 (%)a

Grade 2 (%)a

Grade 3 (%)a

P

Biochemistry

N = 81

N = 15

N = 4

 

Serum CgA

26 (32)

9 (60)

1 (25)

0.09

Urine 5-HIAA

20 (25)

10 (67)

1 (25)

0.007

Imaging

N = 81

N = 15

N = 4

 

CT

35 (43)

8 (53)

2 (50)

0.77

MRI

6 (7)

5 (33)

3 (75)

< 0.001

SRS

19 (24)

3 (20)

1(25)

1.00

MIBG

3 (4)

0 (0)

0 (0)

1.00

18F-FDG PET/CT

2 (3)

1 (7)

1 (25)

0.08

  1. aMissing data present; CgA chromogranin A; 5-HIAA 5-hydroxyindoleacetic acid; CT computed tomography; MRI magnetic resonance imaging; SRS somatostatin receptor scintigraphy; MIBG metaiodobenzylguanidine; 18F-FDG PET/CT fluorodeoxyglucose positron emission tomography; p < 0.05