Table 2 Platinum resistance gene IHC score* in epithelial ovarian cancer
IHC score | Sen-group(n/%) | Res-group(n/%) | p | |
|---|---|---|---|---|
CXCL1 | 0 | 39(90.70) | 9(33.3) | 0.000 |
1+ | 4(9.3) | 16(59.3) | ||
2+ | 0(0) | 2(7.4) | ||
CXCL2 | 0 | 33(76.7) | 7(25.9) | 0.000 |
1+ | 10(23.3) | 17(63.0) | ||
2+ | 0(0) | 3(11.1) | ||
IL6 | 0 | 32(74.4) | 4(14.8) | 0.000 |
1+ | 11(25.6) | 14(51.9) | ||
2+ | 0(0) | 9(33.3) | ||
DUSP1 | 0 | 35(81.4) | 14(51.9) | 0.006 |
1+ | 8(18.6) | 10(37) | ||
2+ | 0(0) | 3(11.1) | ||
NFKBIZ | 0 | 38(88.4) | 15(55.6) | 0.002 |
1+ | 5(11.6) | 12(44.4) | ||
CTR1 | 0 | 13(30.2) | 18(66.7) | 0.000 |
1+ | 18(41.9) | 9(33.3) | ||
2+ | 12(27.9) | 0(0) | ||
P-gp | 0 | 33(76.7) | 10(37.0) | 0.000 |
1+ | 10(23.3) | 12(44.4) | ||
2+ | 0(0) | 5(18.6) | ||
ABCC1 | 0 | 40(93.0) | 15(55.6) | 0.000 |
1+ | 3(7.0) | 12(44.4) | ||
BCRP | 0 | 35(81.4) | 10(37.0) | 0.000 |
1+ | 8(18.6) | 15(55.6) | ||
2+ | 0(0) | 2(7.4) | ||
LRP | 0 | 32(74.4) | 7(26.0) | 0.000 |
1+ | 11(25.6) | 10(37.0) | ||
2+ | 0(0) | 10(37.0) | ||
BCL2 | 0 | 36(83.7) | 8(29.6) | 0.000 |
1+ | 7(16.3) | 16(59.3) | ||
2+ | 0(0) | 3(11.1) | ||
P53 | 0 | 36(83.7) | 11(40.7) | 0.000 |
1+ | 7(16.3) | 14(51.9) | ||
2+ | 0(0) | 2(7.4) | ||
Survivin | 0 | 35(81.4) | 15(55.6) | 0.018 |
1+ | 8(18.6) | 11(40.7) | ||
2+ | 0(0) | 1(3.7) | ||
ERCC1 | 0 | 33(76.7) | 7(25.9) | 0.000 |
1+ | 10(23.7) | 15(55.6) | ||
2+ | 0(0) | 5(18.5) | ||