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Table 1 Clinical characteristics of epithelial ovarian cancer patients in training cohort (n = 70)

From: Enhancing precision medicine: a nomogram for predicting platinum resistance in epithelial ovarian cancer

Clinical features

Sen-group(n = 43) (n/%)/\(\bar {x} \pm s\)

Res-group(n = 27) (n/%)/\(\bar {x} \pm s\)

t/χ2

p

Age

    

 ≤ 50 years

19(44.2)

5(18.5)

4.850

0.028

 > 50years

24(55.8)

22(81.5)

Maximum tumor diameter

    

 ≤ 5 cm

13(30.2)

13(48.1)

2.280

0.131

 > 5 cm

30(69.8)

14(51.9)

FIGO stage

    

 I/II

12(27.9)

3(11.1)

2.779

0.096

 III/IV

31(72.1)

24(88.9)

Histopathological type

    

 serous

36(83.7)

25(92.6)

1.165

0.280

 others

7(16.3)

2(7.4)

Tumor grade

    

 G3

32(74.4)

23(85.2)

1.142

0.285

 G1-G2

11(25.6)

4(14.8)

Lymph node metastasis

    

 unresected

18(41.9)

13(48.1)

6.534

0.038

 no

14(32.6)

2(7.4)

 yes

11(25.6)

12(44.4)

Vascular cancer thrombus

    

 no

32(74.4)

10(37.0)

9.657

0.002

 yes

11(25.6)

17(63.0)

Ascites cancer cell

    

 no

22(51.2)

4(14.8)

9.386

0.002

 yes

21(48.8)

23(85.2)

Residual tumor size*

    

 R0

27(62.8)

11(40.7)

4.717

0.095

 R1

13(30.2)

10(37.0)

 R2

3(7.0)

6(22.2)

Neoadjuvant chemotherapy

    

 no

36(83.7)

11(40.7)

13.888

0.000

 yes

7(16.3)

16(59.3)

CA125(U/L)

874.35 ± 1268.85

1558.4 ± 1632.69

2.655

0.054

HE4(pmol/L)

313.06 ± 263.33

606.15 ± 356.95

-3.945

0.000

  1. p < 0.05 were considered statistically signifcant
  2. *Residual tumor size: R0 = total tumor resection, R1 = microscopic residual, R2 = gross residual