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Table 1 Characteristics of the included studies

From: Is there any difference in urinary continence between bilateral and unilateral nerve sparing during radical prostatectomy? A systematic review and meta-analysis

Study, year

Sample size

Surgical approach

Age, yr, mean or median

Timing of outcome, mo

Continence definition

Prospective

 Albayrak 2010 [10]

BNS 73, UNS 12

Perineal

62

3

No pad

 Asimakopoulos 2019 [11]

BNS 69, UNS 10

RARP

65

Immediate

No pad

 Avulova 2018 [12]

BNS 805, UNS 186

80% RARP, 19% ORP, 1% other

BNS 61, UNS 63

36

No pad

 Berg 2014 [13]

BNS 85, UNS 72

RARP

BNS 60, UNS 63

3, 6, 12, 24

No pad

 Berry 2009 [14]

BNS 341, UNS 89

65%RARP, 12% LRP, 23% ORP

BNS 59, UNS 59

36

Return to 75% of baseline continence score (UCLA-PCI)

 Bhat 2022 [15]

BNS 1308, UNS 532

RARP

51

12

No pad

 Budaus 2009 [16]

BNS 464, UNS 173

Retropubic

63

12

0–1 pad per day

 Burkhard 2006 [17]

BNS 75, UNS 322

Retropubic

64

12

No pad

 Choi 2011 [18]

BNS 469, UNS 89

RARP

BNS 58, UNS 59

4, 12, 24

No pad

 Collette 2021 [19]

BNS 990, UNS 466

RARP

66

12

0–1 pad per day

 d’Altilia 2022 [20]

BNS 120, UNS 49

59%RARP; 41% ORP

66

3, 6, 12

24-h pad test ≤ 20g/day

 Dalkin 2006 [21]

BNS 53, UNS 68

Retropubic

63

12, 24

No pad

 El-Hakim 2015 [22]

BNS 167, UNS 28

RARP

60

3

No pad

 Feng 2020 [23]

BNS 187, UNS 84

RARP

62

15

No pad

 Fossati 2017 [24]

BNS 1351, UNS 144

RARP

63

12

No pad

 Geraerts 2013 [25]

BNS 112, UNS 44

36%RARP, 64%ORP

62

12

0 g urine leakage

 Hatiboglu 2015 [26]

BNS 697, UNS 202

57%RARP, 43%Retropubic

64

Immediate

No pad

 Hinata 2014 [27]

BNS 35, UNS 92

RARP

BNS 62, UNS 63

1, 3, 6

No pad

 Holze 2019 [28]

BNS 153, UNS 57

46.2%RARP, 53.8%ORP

65

3

No pad

 Kim 2019 [29]

BNS 285, UNS 214

RARP

65

1, 3, 6, 12

No pad and no leakage

 Ko 2012 [30]

BNS 779, UNS 394

RARP

60

1.5, 3, 6

No pad and no leakage

 Kohjimoto 2022 [31]

BNS 92, UNS 199

RARP

69

1, 3, 6, 12, 24

No pad

 Kováčik 2019 [32]

BNS 60, UNS 28

RARP

64

0.5, 3, 6, 12

0–1 pad per day

 Kowalczyk 2013 [33]

BNS 490, UNS 120

RARP

60

5, 12

No pad

 Kung 2015 [34]

BNS 33, UNS 10

Retropubic

60

57

No pad

 Lavigueur-Blouin 2015 [35]

BNS 201, UNS 52

RARP

60

1

No pad

 Lee 2010 [36]

BNS 58, UNS 15

RARP

59

1.5

No pad

 Marien 2008 [37]

BNS 538, UNS 72

Retropubic

BNS 57, UNS 59

24

Total control or occasional leakage

 Nandipati 2007 [38]

BNS 66, UNS 25

ORP

BNS 62, UNS 64

3, 6, 12, 24, > 60

No pad

 Novara 2010 [39]

BNS 201, UNS 22

RARP

62

12

No leakage

 Nyarangi-Dix 2020 [40]

BNS 156, UNS 86

RARP

65

12, 24

No pad

 Pagliarulo 2020 [41]

BNS 163, UNS 68

LRP

65

12

No pad

 Pick 2011 [42]

BNS 357, UNS 143

RARP

BNS 60, UNS 63

1, 3, 12

No pad

 Reichert 2022 [43]

BNS 25, UNS 27

RARP

64

12

No pad

 Rigatti 2012 [44]

BNS 24, UNS 9

RARP

66

1, 3

No leakage

 Sammon 2013 [45]

BNS 1015, UNS 125

RARP

60

Immediate

No pad

 Scarcia 2018 [46]

BNS 208, UNS 201

RARP

65

1, 3, 12

0–1 pad per day

 Steineck 2015 [47]

BNS 970, UNS 959

78%RARP, 22%ORP

63

12

No pad

 Suardi 2012 [48]

BNS 900, UNS 49

Retropubic

64

12, 24

No pad

 Talcott 1997 [49]

BNS 28, UNS 38

ORP

BNS 61, UNS 62

3, 12

No pad

 Theissen 2019 [50]

BNS 76, UNS 23

50%RARP, 50%ORP

66

Immediate

Urine loss (≤ 10g) within 1h

 Toren 2009 [51]

BNS 159, UNS 32

ORP

BNS 59, UNS 60

12

No or rare urine leakage

 Tsikis 2017 [52]

BNS 396, UNS 51

RARP

58

12

No pad

 Tzou 2009 [53]

BNS 73, UNS 112

Retropubic

63

12, 24

No pad

 Van der Poel 2009 [54]

BNS 61, UNS 72

RARP

60

6

No involuntary urine loss

 Van der Slot 2023 [55]

BNS 340, UNS 202

RARP

68

6, 12, 24

0–1 pad per day

Retrospective

 Chung 2020 [56]

BNS 125, UNS 72

70%RARP, 30%ORP

68

12

No pad

 Fosså 2019 [57]

BNS 165, UNS 242

RARP

62

24

No pad

 Greco 2011 [58]

BNS 250, UNS 207

Extraperitoneal LRP

BNS 59, UNS 60

1, 3, 12

No pad

 Hinata 2019 [59]

BNS 46, UNS 137

RARP

BNS 65, UNS 66

24

No pad

 Kadono 2015 [60]

BNS 15, UNS 36

RARP

BNS 64, UNS 65

12

24-h pad test ≤ 2g/day

 Lee 2013 [61]

BNS 100, UNS 54

Extraperitoneal LRP

66

3

No pad

 Noël 2022 [62]

BNS 391, UNS 138

RARP

57

1.5

No leakage

 Palisaar 2015 [63]

BNS 1332, UNS 687

RARP or ORP

64

1.5

0–1 pad per day

 Punnen 2014 [64]

BNS 157, UNS 74

RARP

NA

6

No pad

 Shikanov 2011 [65]

BNS 1021, UNS 322

RARP

60

12

No pad

 Wang 2014 [66]

BNS 2, UNS 13

RARP

64

12

No pad

  1. BNS bilateral nerve sparing, UNS unilateral nerve sparing, RARP robot-assisted radical prostatectomy, LRP laparoscopic radical prostatectomy, NA not available, ORP open radical prostatectomy, UCLA-PCI University of California, Los Angeles, Prostate Cancer Index