Table 2 Univariate and multivariate Cox regression analysis in low-risk GIST patients with recurrence or metastasis

Age (%)

 ≤ 60

Reference

 > 60

0.846 (0.282~2.536)

0.766

Gender (%)

 Male

Reference

 Female

0.482 (0.161~1.437)

0.190

Tumor site (%)

 Stomach

Reference

Reference

 No stomach

5.930 (1.844~19.072)

0.003

4.290 (1.307~14.082)

0.016

Resection type(%)

 Laparoscopic resection

Reference

Reference

 Open resection

4.759 (1.063~21.306)

0.041

2.418 (0.420~13.926)

0.323

Tumor size (%)

 <4 cm

Reference

Reference

 ≥4 cm

4.852 (1.353~17.397)

0.015

4.987 (1.383~17.989)

0.014

CD117 (%)

  (-)

Reference

  (+)

0.429 (0.047~3.917)

0.453

  (++)

0.244 (0.022~2.706)

0.250

  (+++)

0.307 (0.037~2.546)

0.274

CD34 (%)

  (-)

Reference

Reference

  (+)

0.129 (0.024~0.704)

0.018

0.408 (0.071~2.346)

0.315

  (++)

0.361 (0.080~1.624)

0.184

0.726 (0.144~3.655)

0.698

  (+++)

0.145 (0.039~0.541)

0.004

0.680 (0.144~3.204)

0.626

Dog-1(%)

  (-)

Reference

  (+)

0.178 (0.024~1.296)

0.088

  (++)

0.680 (0.113~4.080)

0.673

  (+++)

0.288 (0.059~1.403)

0.123

Ki-67 index (%)

 ≤ 5 %

Reference

Reference

 > 5 %

9.730 (2.253~29.106)

< 0.001

8.198 (2.680~25.007)

< 0.001

PLR(%)

 ≤153.31

Reference

 >153.31

1.876 (0.658~5.352)

0.239

NLR(%)

 ≤2.81

Reference

Reference

 >2.81

3.152 (1.104~8.996)

0.032

1.150 (0.344~3.849)

0.820

Gastrointestinal bleeding(%)

 Yes

Reference

 None

1.857 (0.582~5.924)

0.296

Basic disease(%)

 Yes

Reference

 None

1.148 (0.384~3.428)

0.805