Table 2 Univariate and multivariate analysis for overall survival in all patients

Gender

 Female

1

 Male

0.83 (0.62–1.10)

0.198

Age (years)

 < 65

1

 ≥ 65

0.90 (0.68–1.20)

0.484

Tumor length (cm)

 < 3

1

 ≥ 3

0.95 (0.70–1.30)

0.765

Vessel invasion

 Negative

1

 Positive

1.06 (0.71–1.58)

0.769

Perineural invasion

 Negative

1

 Positive

1.26 (0.90–1.76)

0.185

Tumor location

 Upper

1

 Middle

1.02 (0.64–1.62)

0.939

 Lower

0.90 (0.55–1.47)

0.677

Differentiation

 Well

1

1

 Moderate

1.48 (0.95–2.31)

0.081

1.39 (0.89–2.18)

0.151

 Poor

2.32 (1.40–3.83)

0.001

1.94 (1.16–3.24)

0.012

TNM

 I

1

1

 II

1.28 (0.88–1.86)

0.203

1.21 (0.83–1.77)

0.322

 III

1.73 (1.18–2.53)

0.005

1.51 (1.02–2.23)

0.039

Adjuvant treatment

 Yes

1

 No

1.32 (0.96–1.82)

0.089

NPS

 0

1

1

 1

1.54 (1.03–2.29)

0.034

1.42 (0.95–2.12)

0.091

 2

2.09 (1.39–3.15)

 < 0.001

1.70 (1.11–2.59)

0.014

Albumin (g/L)

 < 35

 ≥ 35

0.71 (0.50–1.01)

0.058

PNI

 < 46

1

1

 ≥ 46

0.63 (0.46–0.85)

0.003

0.71 (0.52–0.98)

0.036

COUNT

 Normal/light

1

 Moderate

1.22 (0.97–1.45)

0.064

MAI

 Unbalance

1

1

 Balance

0.64 (0.48–0.85)

0.002

0.67 (0.50–0.90)

0.007