Table 3 Univariate and multivariate analysis of DSS

Age (older/younger)

1.540 (1.229, 1.929)

< 0.001*

1.718 (1.369, 2.157)

< 0.001*

Sex (male/female)

1.249 (0.992, 1.573)

0.059

1.041 (0.823, 1.318)

0.736

BMI

0.987 (0.954, 1.021)

0.451

0.982 (0.947, 1.017)

0.307

Diabetes mellitus (yes/no)

1.228 (0.923, 1.635)

0.159

0.934 (0.684, 1.276)

0.668

Hypertension (yes/no)

1.106 (0.858, 1.425)

0.437

1.078 (0.808, 1.438)

0.384

Tumor location (rectum/colon)

0.996 (0.753, 1.318)

0.978

1.103 (0.829, 1.467)

0.502

Tumor differentiation (low/medium/high)

2.392 (1.924, 2.973)

< 0.001*

1.522 (1.211, 1.913)

< 0.001*

Tumor pathological stage (0/I/II/III/IV)

2.538 (2.182, 2.952)

< 0.001*

2.071 (1.762, 2.434)

< 0.001*

Surgical characteristic (R2/R1/R0)

2.236 (1.986, 2.517)

< 0.001*

1.578 (1.382, 1.801)

< 0.001*

Adjuvant chemotherapy (yes/no)

1.298 (0.986, 1.708)

0.063

0.974 (0.723, 1.312)

0.862

Adjuvant radiotherapy (yes/no)

2.521 (1.189, 5.344)

0.016*

0.923 (0.420, 2.025)

0.841