Table 2 Multivariate analysis of predictive factors for STR among 296 RPLS cases

Demographic characteristics

 Preoperative NLR

0.121

1.129 (1.035–1.232)

0.007

 Smoking history

-0.685

0.504 (0.238–1.069)

0.074

 Diabetes

-1.945

0.143 (0.031–0.659)

0.013

Surgical characteristics

 Surgical frequency

0.038

  2nd time vs. 1st time

0.272

1.313 (0.582–2.960)

0.511

  ≥ 3rd time vs. 1st time

0.971

2.642 (1.180–5.913)

0.018

  Combined organ excision

-0.189

0.828 (0.421–1.626)

0.583

  Operative time

0.001

1.001 (0.997–1.005)

0.717

  Intraoperative blood loss

 < 0.001

1.000 (1.000–1.001)

0.235

  Transfer to ICU

0.871

2.390 (1.200–4.760)

0.013

Pathological characteristics

  Multiple primary tumors

0.719

2.052 (1.039–4.054)

0.038

  Irregular tumor shape

0.410

1.507 (0.815–2.788)

0.191

  Intact tumor capsule

-0.694

0.499(0.267–0.936)

0.030

Histological subtype

 < 0.001

 De-differentiated vs. well-differentiated

2.239

9.381(3.585–24.548)

 < 0.001

 Other subtypes vs. well-differentiated

1.040

2.831(1.326–6.043)

0.007

 Tumor necrosis

0.757

2.131 (1.007–4.511)

0.048

 Constant values

-2.660

0.070

 < 0.001