Characteristic | LS group (n = 40) | OS group (n = 28) | p-value |
---|---|---|---|
Gender, n (%) | |||
Male | 22 (55.0) | 21 (75.0) | 0.127 |
Female | 18 (45.0) | 7 (25.0) | |
Age, years, median (IQR) | 63 (53.5–68) | 64.5 (57.0–69.75) | 0.403 |
BMI, kg/m2 | 22.5 (20.76–23.60) | 21.9 (19.76–24.75) | 0.596 |
ECOG-PS, n (%) | |||
0 | 9 (22.5) | 8 (28.57) | 0.393 |
1 | 25 (62.5) | 13 (46.43) | |
2 | 6 (15.0) | 7 (25.0) | |
ASA score, n (%) | |||
I | 13 (32.5) | 1 (3.57) | 0.002* |
II | 19 (47.5) | 12 (42.86) | |
III | 8 (20.0) | 15 (53.57) | |
Child-Pugh classification | |||
B | 32 (80.0) | 15 (53.57) | 0.032* |
C | 8 (20.0) | 13 (46.43) | |
Comorbidity, n (%) | |||
Diabetes | 2 (5.0) | 3 (10.7) | 0.396 |
Hypertension | 8 (20.0) | 2 (7.14) | 0.179 |
Cardiac insufficiency | 3 (7.5) | 2 (7.14) | > 0.999 |
Pulmonary insufficiency | 1 (2.5) | 2 (7.14) | 0.564 |
Cerebrovascular disease | 0 | 1 (3.57) | 0.412 |
Viral hepatitis | 5 (12.5) | 1 (3.57) | 0.389 |
Cirrhosis | 3 (7.50) | 2 (7.14) | > 0.999 |
Gallstones | 5 (12.5) | 3 (10.71) | > 0.999 |
Cholecystitis | 3 (7.50) | 7 (25.0) | 0.079 |
Previous abdominal surgery, n (%) | 6 (15.0) | 5 (17.86) | 0.751 |
Preoperative biliary drainage, n (%) | |||
PTCD | 22 (55.0) | 12 (42.86) | 0.460 |
ERCP | 0(0) | 1 (3.57) | 0.412 |
Preoperative liver function | |||
ALT, U/L | 64.5 (35.75–127.5) | 83.7 (50–134.75) | 0.419 |
AST, U/L | 60 (41–101.5) | 65.7 (45.85–107.25) | 0.414 |
GGT, U/L | 205.85 (114.5–652) | 548.1 (307.25–854.5) | 0.006* |
DBIL, μmol/L | 91.3 ± 68.34 | 97.39 ± 61.12 | 0.702 |
TBIL, μmol/L | 143.1 ± 100.39 | 148.2 ± 83.37 | 0.826 |
ALB, g/L | 38.95 (34.725–42.2) | 38.65 (34.0–41.0) | 0.529 |
ALP, U/L | 279 (212–597.75) | 416.8 (232.8–637.25) | 0.124 |
Preoperative coagulation function | |||
APTT, s | 34.52 ± 4.89 | 35.46 ± 5.33 | 0.453 |
FIB, g/L | 4.22 (3.65–4.89) | 4.56 (3.62–5.53) | 0.246 |
INR | 0.97 (0.91–1.0325) | 0.935 (0.9025–1.015) | 0.685 |
PT, s | 12.55 (11.625–13.1) | 12.5 (11.7–13.5) | 0.774 |
Preoperative tumor markers | |||
CA-199, U/mL | 270.8 (36.10–2581.14) | 330.8 (76.46–1385.5) | 0.975 |
CEA, μg/L | 2.235 (0.925–5.808) | 2.140 (1.013–4.488) | 0.627 |
AFP, μg/L | 2.55 (0.90–6.30) | 2.16 (1.62–3.865) | 0.831 |