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Table 2 Univariate analyses of mortality and morbidity following resection surgery, marginal matched, and caliper matched groups. Multivariable analyses of mortality and morbidity after resection surgery, all subjects. stratified by age

From: Mortality and morbidity after colorectal cancer resection surgery in elderly patients: a retrospective population-based study in Sweden

Variables

Marginal matched groups

Caliper matched groups

Multivariable analyses — all subjects

 

 < 70 years (n = 1471)

 ≥ 70 years (n = 1578)

MPD (95% CI), p-value

Effect size

 < 70 years (n = 1236)

 ≥ 70 years (n = 1236)

MPD (95% CI), p-value

Effect size

OR (95% CI), p-value

90-day mortality

 Yes

20 (1.4)

50 (3.2)

1.8 (0.7–2.9), 0.0011

0.12

15 (2.1)

33 (2.7)

1.5 (0.3–2.6), 0.012

0.11

2.12 (1.26–3.58), 0.005

Surgical complications

 Yes

255 (17.3)

228 (14.4)

 − 2.9 (− 5.6–( −)0.2), 0.033

0.08

215 (17.4)

167 (13.5)

 − 3.9 (− 6.8–( −)1.0), 0.009

0.11

0.84 (0.69–1.03), 0.096

Complications requiring treatment

 Yes

518 (35.4)

538 (34.3)

 − 1.1 (− 4.6–2.3), P 0.54

0.02

418 (34.0)

420 (34.2)

0.1 (− 3.7–4.0), 0.98

0.00

0.98 (0.84–1.15), 0.81

ICU care

 Yes

73 (5.0)

91 (5.8)

0.8 (− 0.9–2.5), P 0.38

0.04

54 (4.4)

56 (4.6)

0.1 (− 1.6–1.9), 0.94

0.01

1.01 (0.73–1.39), 0.97

Reoperation

 Yes

129 (8.8)

125 (8.0)

0.9 (− 2.9–1.2), P 0.42

0.03

110 (9.0)

98 (8.0)

 − 1.0 (− 3.3–1.3), 0.41

0.04

0.95 (0.73–1.23), 0.68

Readmission

 Yes

156 (10.7)

137 (8.7)

 − 1.9 (− 4.1–0.2) P 0.081

0.07

124 (10.1)

109 (8.9)

 − 1.2 (− 3.6–1.2), 0.33

0.04

0.81 (0.63–1.03), 0.08

1-year mortality

 Yes

68 (4.6)

136 (8.6)

4.0 (2.2–5.8), P < 0.001

0.16

55 (4.4)

96 (7.8)

3.3 (1.4–5.3), 0.0007

0.14

1.89 (1.38–2.60), < 0.0001

  1. Variables presented as n (%). Univariate analyses were conducted using Fisher’s exact test, values expressed as MPD (95% CI) and effect size (absolute difference in mean SD). Multivariate analyses were made using a multivariable logistic regression model, adjusted for sex, ASA grade, elective vs urgent procedure, TNM stage, tumour location and intra-operative bleeding, values expressed as OR (95% CI)
  2. Abbreviations: ASA American Society of Anaesthesiologists, CI confidence interval, ICU intensive care unit, MPD mean percent difference, OR odds ratio, SD standard deviation