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Table 2 Major clinicopathological characteristics of MPM patients between PS and non-PS groups

From: Risk factors and prognosis of malignant peritoneal mesothelioma with paraneoplastic syndrome

Variables

Non-PS group (n = 86)

PS group (n = 60)

P value

Gender, n (%)

0.875

 Female

47 (54.7)

32 (53.3)

 

 Male

39 (45.3)

28 (46.7)

 

Age (years), n (%)

0.873

  < 60

57 (66.3)

39 (65.0)

 

  ≥ 60

29 (33.7)

21 (35.0)

 

BMI (kg/m2), n (%)

0.156

  < 18.5

5 (5.8)

8 (13.3)

 

 18.5–23.9

45 (52.3)

34 (56.7)

 

  ≥ 24.0

36 (41.9)

18 (30.0)

 

History of surgery, n (%)

0.198

 No

31 (36.0)

28 (46.7)

 

 Yes

55 (64.0)

32 (53.3)

 

Previous surgical score, n (%)

0.027

 0/1

63 (73.3)

53 (88.3)

 

 2/3

23 (26.7)

7 (11.7)

 

History of chemotherapy, n (%)

0.321

 No

43 (50.0)

25 (41.7)

 

 Yes

43 (50.0)

35 (58.3)

 

History of radiotherapy, n (%)

0.133

 No

86 (100.0)

57 (95.0)

 

 Yes

0 (0.0)

3 (5.0)

 

History of targeted therapy, n (%)

0.049

 No

51 (59.3)

45 (75.0)

 

 Yes

35 (40.7)

15 (25.0)

 

KPS, n (%)

0.035

 < 80

6 (7.0)

11 (18.3)

 

 ≥ 80

80 (93.0)

49 (81.7)

 

Pathological type, n (%)

0.880

 Epithelioid type

65 (75.6)

46 (76.7)

 

 Non-epithelioid type

21 (24.4)

14 (23.3)

 

Vascular tumor emboli, n (%)

0.005

 No

73 (84.9)

39 (65.0)

 

 Yes

13 (15.1)

21 (35.0)

 

Lymphatic metastasis, n (%)

0.819

 No

77 (89.5)

53 (88.3)

 

 Yes

9 (10.5)

7 (11.7)

 

Ki-67 index, n (%)

0.835

 ≤ 9%

14 (16.3)

9 (15.0)

 

 > 9%

72 (83.7)

51 (85.0)

 

Preoperative CA 125 level (U/mL), n (%)

0.004

 Normal

35 (40.7)

11 (18.3)

 

 Increased

51 (59.3)

49 (81.7)

 
  1. MPM malignant peritoneal mesothelioma, PS paraneoplastic syndrome, BMI body mass index, KPS Karnofsky performance status score