Fig. 4

Mutant proteins analysis. (1) MSH6 protein analysis. A Region 92–154, PWWP domain; B Region 1–84, disordered; C Region 195–362, disordered; D NP_BIND 1134–1141, ATP; E MOD_RES 488–488, phosphothreonine; F MOD_RES 504–504, N6-acetyllysine; G MOD_RES 830–830, phosphoserine; H MOD_RES 935–935, phosphoserine; I MOD_RES 1010–1010, phosphothreonine. (2) MLH1 protein analysis. J Region 355–378, disordered; K Region 400–491, disordered; L Region 410–650, Interaction with EXO1; M NP_BIND 82–84, ATP; N NP_BIND 100–104, ATP; O BINGDING 38–38, ATP; P BINGDING 63–63, ATP; Q MOD_RES 2–2, N-acetylserine; R MOD_RES 477–477, phosphoserine