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Table 2 Next-generation sequencing: the top ten most frequently mutated genes and HRD and MSI status in EOC patients

From: CD47—a novel prognostic predicator in epithelial ovarian cancer and correlations with clinicopathological and gene mutation features

Genes, number (%)

 TP53

54 (72.0)

 BRCA1

15 (20.0)

 PIK3CA

13 (17.3)

 BRCA2

8 (10.7)

 MYC

9 (12.0)

 KRAS

8 (10.7)

 NF1

8 (10.7)

 ARID1A

7 (9.3)

 CDKN2A

6 (8.0)

 PMS2

6 (8.0)

HRD statusa, number (%)

 Negative

20 (39.4)

 Positive

35 (63.6)

MSI status, number (%)

 MSS/MSI-L

70 (93.3)

 MSI-H

5 (6.7)

  1. aHRD status was not detected in 20 patients