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Table 4 Stratified analysis of NSLN metastases

From: Association between postoperative pathological results and non-sentinel nodal metastasis in breast cancer patients with sentinel lymph node-positive breast cancer

Variables

Number SNM(n = 1)

Number SNM(n > 1)

OR(95%CI)

total

metastasis

total

metastasis

Crude

Mutually adjusted

Age

 ≤ 50

71

19

72

48

5.47 (2.67, 11.23)

4.13 (1.74, 9.82)

  > 50

84

26

53

33

3.68 (1.79, 7.58)

4.28 (1.82, 10.11)

BMI

  ≤ 25

109

33

88

59

4.69 (2.56, 8.57)

4.10 (2.03, 8.31)

  > 25

46

12

37

22

4.16 (1.64, 10.53)

4.51 (1.50, 13.60)

Tumor size (cm)

  ≤ 2

65

15

28

17

5.15 (1.99, 13.36)

5.37 (1.77, 16.31)

  > 2

90

30

97

64

3.88 (2.11, 7.12)

3.88 (1.88, 8.02)

Histological stage

 Midddle/low

126

36

105

71

5.22 (2.97, 9.16)

4.86 (2.54, 9.30)

 High

15

6

10

3

0.64 (0.12, 3.53)

inf

Ki-67

 Negative

113

29

90

59

5.51 (3.01, 10.11)

4.75 (2.37, 9.54)

 Positive

41

16

34

22

2.86 (1.12, 7.35)

4.53 (1.27, 16.20)

HER2

 Negative

123

33

92

55

4.05 (2.28, 7.22)

3.36 (1.74, 6.51)

 Positive

31

12

32

25

5.65 (1.87, 17.10)

11.68 (2.01, 67.82)

ER

 Negative

27

6

20

15

10.50 (2.70, 40.88)

26.73 (2.16, 331.09)

 Positive

128

39

105

66

3.86 (2.24, 6.67)

3.41 (1.81, 6.42)

PR

 Negative

45

11

32

23

7.90 (2.83, 22.07)

7.37 (1.85, 29.38)

 Positive

110

34

93

58

3.70 (2.07, 6.63)

3.32 (1.71, 6.46)

LVI

 Negative

89

14

47

18

3.33 (1.47, 7.55)

2.81 (1.17, 6.73)

 Positive

66

31

78

63

4.74 (2.26, 9.96)

5.07 (2.18, 11.81)

menopause

 No

81

20

82

54

5.88 (2.98, 11.62)

5.39 (2.44, 11.87)

 Yes

74

25

43

27

3.31 (1.51, 7.24)

3.60 (1.33, 9.71)

  1. Each stratification adjusted for all the factors (Age, BMI, ER, HER2, Histological stage, Ki-67, PR, LVI, menopause and Tumor size) except the stratification factor itself
  2. BMI body mass index, Number SLNM the number of sentinel lymph node metastases, HER2 human epidermal growth factor Receptor 2, ER estrogen receptor, PR progesterone receptor, LVI lymphovascular invasion