Table 3 Cox proportional hazard regression analysis of overall survival in patients diagnosed with stage IA micropapillary non-predominant lung adenocarcinoma with a micropapillary component > 5%

Age

1.141

1.012–1.286

0.032

1.113

0.980–1.265

0.100

Sex

 Female

Ref

 Male

0.801

0.179–3.583

0.772

Smoking history

 Non-smoker

Ref

 Smoker

0.528

0.064–4.389

0.555

Surgical procedure

 Open

Ref

 VATS

0.513

0.099–2.647

0.425

Resection range

 Sublobar resection

Ref

 Lobectomy

1.053

0.127–8.755

0.962

Surgical side

 Left

Ref

 Right

2.142

0.413–11.108

0.364

Number of LN dissected

1.035

0.944–1.134

0.467

Tumor size

5.601

1.201–26.114

0.028

4.591

0.931–22.635

0.061

Micropapillary component

0.968

0.873–1.072

0.533

Papillary component

1.000

0.975–1.026

0.986

Solid component

0.917

0.703–1.197

0.525

Acinar component

0.973

0.943–1.004

0.087

0.982

0.945–1.020

0.350

Lepidic component

1.026

1.007–1.046

0.007

1.015

0.992–1.038

0.208

Lymphovascular invasion

 No

Ref

 Yes

0.045

0–71934.377

0.670

Spread through air spaces

 No

Ref

 Yes

0.039

0–1043.832

0.533

pTNM stage

 IA1

Ref

 IA2

5281.969

0–2.541E + 149

0.960

 IA3

17,160.754

0–8.243E + 149

0.955

Adjuvant chemotherapy

 No

Ref

 Yes

0.016

0.000–6.789

0.179