World Journal of Surgical Oncology

Table 2 The pooled analysis of OS from different NCBD database studies

From: Effect of adjuvant chemotherapy on the oncological outcome of rectal cancer patients with pathological complete response

Hazard ratio of OS						5-years OS rate
Study	HR	95% CI		I² (%)	P	Study	OR	95% CI		I²	P
Study	HR	LCI	UCI	I² (%)	P	Study	OR	LCI	UCI	I²	P
All [18, 26, 29, 31, 35, 38, 39, 43, 47]	0.65	0.57	0.74	46	< 0.001^*	All [18, 26, 29, 31, 35, 38, 39, 43]	1.890	1.623	2.198	49.8	< 0.001^*
Lai et al. [19]	0.803	0.678	0.952	0	0.011	Lai et al [19]	1.605	1.182	2.179	39.3	0.002^*
Bliggenstorfer et al. [26]	0.756	0.633	0.903	25.8	0.002	Bliggenstorfer et al. [26]	1.626	1.179	2.242	43	0.003^*
Naffouje et al. [29]	0.812	0.716	0.921	0	0.001	Naffouje et al. [29]	1.543	1.159	2.053	34.9	0.003^*
Morris et al. [18]	0.776	0.658	0.914	0	0.002	Morris et al. [18]	1.600	1.185	2.160	38.7	0.002^*
Gahagan et al. [31]	0.790	0.694	0.9	0	< 0.001	Gahagan et al. [31]	1.546	1.175	2.033	34.9	0.002^*
Dossa et al. [35]	0.774	0.648	0.925	13.9	0.005	Dossa et al. [35]	1.626	1.175	2.252	43	0.003^*
Polanco et al. [38]	0.662	0.577	0.76	36	< 0.001	Polanco et al. [38]	1.616	1.176	2.222	41.1	0.003^*
Turner et al. [39]	0.831	0.729	0.947	0	0.005	Turner et al. [39]	1.567	1.189	2.066	35.4	0.001^*
Shahab et al. [43]	0.82	0.68	0.98	0	0.031	Shahab et al. [43]	1.650	1.168	2.331	52.1	0.004^*
Xu et al. [47]	0.784	0.654	0.941	13.9	0.009

*random effects model; HR hazard ratio, OR odds ratio, CI confidence interval, LCI low confidence interval, UCI upper confidence interval, OS overall survival

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