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Table 3 Prediction of axillary lymph node (ALN) burden

From: Reliability of predicting low-burden (≤ 2) positive axillary lymph nodes indicating sentinel lymph node biopsy in primary operable breast cancer — a retrospective comparative study with PET/CT and breast MRI

Number of positive ALN on imaging

PET/CT

MRI

p-value

(1)

PET/CT + MRI

p-value

(2)

p-value

(3)

 

NPV (%)

NPV (%)

 

NPV (%)

  

0

73.5  (133/181)

80.8  (101/125)

0.138

84  (89/106)

0.041*

0.531

 

PPV (%)

PPV (%)

 

PPV (%)

  

1

24.4  (10/41)

22.5  (9/40)

0.841

44.4  (4/9)

0.25

0.22

2

8.7  (3/23)

30  (6/20)

0.263

33.3  (1/3)

0.4

 > 0.999

1–2 (low burden)

35.9 (23/64)

36.7 (22/60)

0.933

55 (11/20)

0.13

0.149

0–2 (indicator for SLNB)

88.6 (217/245)

95.7 (177/185)

0.008*

96.1 (173/180)

0.005*

0.834

  1. *p-value < 0.05
  2. p-value (1): PET/CT vs MRI, p-value (2): PET/CT vs PET/CT + MRI, p-value (3): MRI vs PET/CT + MRI