Table 1 Univariate and multivariate analysis of early recurrence in patients with gastric cancer in train cohort

Age

 ≤ 60

143

69

Ref

Ref

 > 60

120

33

1.755

1.085 ~ 2.837

0.022

1.789

1.043 ~ 3.068

0.035

Sex

 Female

80

31

Ref

 Male

183

71

1.001

0.609 ~ 1.646

0.996

Tumour length

 < 5cm

107

50

Ref

 ≥ 5cm

156

52

1.402

0.852 ~ 2.220

0.150

Nerve invasion

 Positive

86

33

Ref

 Negative

177

69

0.984

0.604 ~ 1.604

0.949

Serosa infiltration

 Negative

20

21

Ref

Ref

 Positive

243

81

3.150

1.625 ~ 6.107

0.001

2.293

1.093 ~ 4.811

0.028

Neoadjuvant chemotherapy

 Positive

39

22

Ref

 Negative

224

80

1.169

0.832 ~ 1.643

0.368

Postoperative chemotherapy

 Positive

213

73

Ref

 Negative

50

29

1.526

0.899 ~ 1.856

0.085

Histological type

 Adenocarcinoma

172

46

Ref

 SRCC^a

124

23

1.234

0.979 ~ 1.556

0.075

Lymph node staging

 N0/1/2

151

73

Ref

Ref

 N3

112

29

1.867

1.138 ~ 3.062

0.013

2.162

1.225 ~ 3.815

0.008

Differentiated degree

 Medium–High

31

18

Ref

 Low-Medium

232

84

1.604

0.852 ~ 3.018

0.143

Recurrence mode

 Liver

76

11

5.873

2.691 ~ 12.814

0.000

7.031

3.048 ~ 16.218

0.000

 Abdominal

92

31

2.523

1.368 ~ 4.652

0.003

2.713

1.420 ~ 5.184

0.003

 Retroperitoneal LN

20

3

5.667

1.549 ~ 20.725

0.009

5.696

1.498 ~ 21.658

0.033

 Ovary

13

7

1.579

0.566 ~ 4.405

0.383

1.976

0.661 ~ 5.907

0.223

 Loco-regional

22

16

1.169

0.531 ~ 2.575

0.699

1.655

0.704 ~ 3.894

0.248

 Else

40

34

Ref

Ref

CA19-9

 Normal

172

81

Ref

1.186 ~ 3.513

0.010

Ref

1.096 ~ 3.542

0.023

 Abnormal

91

21

2.041

1.970

CA72-4

 Normal

179

81

Ref

Ref

 Abnormal

84

21

1.810

1.049 ~ 3.123

0.033

1.352

0.743 ~ 2.462

0.324