Table 1 Clinicopathologic characteristics of the 4R node dissection and non-dissection groups
From: Clinical value of station 4R node dissection in esophageal squamous cell carcinoma
Variable | Before matching | After matching | ||||
|---|---|---|---|---|---|---|
Dissection (n = 393) | Non-dissection (n = 343) | p | Dissection (n = 226) | Non-dissection (n = 226) | p | |
Sex | 0.654 | 0.823 | ||||
Male | 311 (79.1) | 266 (77.6) | 176 (77.9) | 173 (76.5) | ||
Female | 82 (20.9) | 77 (22.4) | 50 (22.1) | 53 (23.5) | ||
Age (years) | 0.001 | 0.819 | ||||
≤ 65 | 323 (82.2) | 247 (72.0) | 176 (77.9) | 179 (79.2) | ||
> 65 | 70 (17.8) | 96 (28.0) | 50 (22.1) | 47 (20.8) | ||
Tumor location | 0.018 | 0.849 | ||||
Upper | 58 (14.8) | 58 (16.9) | 39 (17.3) | 44 (19.5) | ||
Middle | 278 (70.7) | 211 (61.5) | 152 (67.3) | 148 (65.5) | ||
Lower | 57 (14.5) | 74 (21.6) | 35 (15.5) | 34 (15.0) | ||
Histologic grade | 0.352 | 0.868 | ||||
G1 | 63 (16.0) | 61 (17.8) | 39 (17.3) | 43 (19.0) | ||
G2 | 218 (55.5) | 172 (50.1) | 116 (51.3) | 116 (51.3) | ||
G3 | 112 (28.5) | 110 (32.1) | 71 (31.4) | 67 (29.6) | ||
Surgical approach | < 0.001 | 0.683 | ||||
Mckeown + 2FL | 259 (65.9) | 281 (81.9) | 180 (79.6) | 187 (82.7) | ||
Akiyama + 3FL | 94 (23.9) | 14 (5.0) | 20 (8.8) | 16 (7.1) | ||
Ivor-lewis | 40 (10.2) | 45 (13.1) | 26 (11.5) | 23 (10.2) | ||
pT stage | 0.098 | 0.783 | ||||
T1a-T1b | 42 (10.7) | 43 (12.5) | 30 (13.3) | 25 (11.1) | ||
T2 | 66 (16.8) | 75 (21.9) | 44 (19.5) | 42 (18.6) | ||
T3 | 274 (69.7) | 210 (61.2) | 145 (64.2) | 149 (65.9) | ||
T4 | 11 (2.8) | 15 (4.4) | 7 (3.1) | 10 (4.4) | ||
pN stage | 0.015 | 0.843 | ||||
N0 | 188 (47.8) | 148 (43.1) | 109 (48.2) | 108 (47.8) | ||
N1 | 106 (27.0) | 110 (32.1) | 66 (29.2) | 72 (31.9) | ||
N2 | 66 (16.8) | 72 (21.0) | 41 (18.1) | 35 (15.5) | ||
N3 | 33 (8.4) | 13 (3.8) | 10 (4.4) | 11 (4.9) | ||
pTNM stage | 0.013 | 0.971 | ||||
0 | 1 (0.3) | 4 (1.2) | 1 (0.4) | 2 (0.9) | ||
Ia | 1 (0.3) | 3 (0.9) | 1 (0.4) | 1 (0.4) | ||
Ib | 36 (9.2) | 35 (10.2) | 26 (11.5) | 20 (8.8) | ||
IIa | 53 (13.5) | 45 (13.1) | 33 (14.6) | 36 (15.9) | ||
IIb | 103 (26.2) | 66 (19.2) | 51 (23.5) | 53 (22.6) | ||
IIIa | 18 (4.6) | 28 (8.2) | 11 (4.9) | 14 (6.2) | ||
IIIb | 146 (37.2) | 146 (42.6) | 91 (40.3) | 87 (38.5) | ||
IVa | 35 (8.9) | 16 (4.7) | 12 (5.3) | 13 (5.8) | ||
Tumor length (mm) | 0.337 | 0.510 | ||||
≤ 35 | 195 (49.6) | 183 (53.4) | 116 (51.3) | 108 (47.8) | ||
> 35 | 198 (50.4) | 160 (46.6) | 110 (48.7) | 118 (52.2) | ||
No. of dissected nodes | 40.2 ± 16.7 | 26.6 ± 11.6 | < 0.001 | 31.5 ± 11.6 | 30.1 ± 12.2 | 0.200 |
Postoperative treatment | 0.430 | 0.976 | ||||
None | 305 (77.6) | 271 (79.0) | 181 (80.1) | 179 (79.2) | ||
Radiotherapy | 1 (0.3) | 4 (1.2) | 1 (0.4) | 1 (0.4) | ||
Chemotherapy | 84 (21.4) | 66 (19.2) | 43 (19.0) | 45 (19.9) | ||
Chemo-radiotherapy | 3 (0.8) | 2 (0.6) | 1 (0.4) | 1 (0.4) | ||