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Table 3 Comparison between the studied groups (IDC and control normal breast tissue groups) regarding β-catenin immunostaining

From: Impact of immunohistochemical expression of kinesin family member 18A (Kif18A) and β-catenin in infiltrating breast carcinoma of no special type

β-catenin

IDC cases (n = 135)

Control normal breast (n = 40)

Test of sig.

p

No.

%

No.

%

Positivity

Membranous

0

0

40

100.0

  

Cytoplasmic

92

68.1

0

0

χ2=175.0*

<0.001*

Nucleocytoplasmic

43

31.9

0

0.0

Percent

Min.–Max.

45.0–95.0

70.0–95.0

U=1688.0*

<0.001*

Mean ± SD.

75.74 ± 11.68

83.37 ± 8.35

Median (IQR)

80.0 (70.0–85.0)

85.0 (75.0–90.0)

Intensity

Mild

13

9.6

0

0.0

χ2=17.949*

<0.001*

Moderate

32

23.7

0

0.0

Strong

90

66.7

40

100.0

Mild + moderate

45

33.3

0

0.0

χ2=17.949*

<0.001*

Strong

90

66.7

40

100.0

H score

Min.–Max.

50.0–285.0

210.0–285.0

U=1322.0*

<0.001*

Mean ± SD.

197.59 ± 63.75

250.13 ± 25.05

Median (IQR)

210.0 (157.5–247.5)

255.0 (225.0–270.0)

Low (<210)

55

40.7

0

0.0

χ2=23.765*

<0.001*

High (>210)

80

59.3

40

100.0

  1. IQR interquartile range, SD standard deviation, U Mann-Whitney test, χ2 chi-square test, FE Fisher’s exact, p p value for comparing between the studied groups
  2. *Statistically significant at p ≤ 0.05