Table 1 Subgroup analysis of the correlation between the expression levels of glycolysis markers and OS according to the specific glycolysis markers, region, sample, and detection method

MLXIPL

1.88 (1.02, 3.47)

NA

GLUT4

1.44 (0.40, 5.20)

NA

PKM2

1.93 (1.70, 2.18)

I² = 0.0%, P = 0.704

MAP17

1.64 (1.36, 1.98)

NA

PFKFB3

2.45 (1.09, 5.52)

NA

STMN1

2.57 (1.43, 4.65)

I² = 49.6%, P = 0.138

PGM1

1.71 (1.11, 2.63)

NA

MCT4

1.64 (1.30, 2.07)

I² = 0.0%, P = 0.755

GLUT1

1.47 (1.05, 2.05)

I² = 44.1%, P = 0.181

CDK1

1.99 (0.37, 10.70)

NA

HK-2

2.12 (1.66, 2.71)

I² = 0.0%, P = 0.604

CA9

2.26 (1.47, 3.47)

I² = 41.1%, P = 0.165

Homer1

1.66 (0.78, 3.54)

NA

ASCT2

1.76 (1.12, 2.76)

NA

LDHB

0.66 (0.46, 0.93)

NA

TRIM35

0.60 (0.39, 0.92)

NA

PGK-1

3.09 (1.31, 7.29)

NA

GLUT2

1.65 (0.86, 3.20)

I² = 0.0%, P = 0.347

China

1.66 (1.43, 1.94)

I² = 67.4%, P < 0.001

Japan

2.37 (1.44, 3.88)

I² = 28.1%, P = 0.234

Germany

1.95 (1.34, 2.83)

I² = 0.0%, P = 0.493

Taiwan

2.70 (1.64, 4.45)

I² = 21.5%, P = 0.280

South Korea

2.19 (1.14, 4.20)

NA

Hong Kong

1.75 (1.02, 3.00)

NA

US

1.86 (1.23, 2.82)

NA

Sample:

Tissue

1.80 (1.57, 2.05)

I² = 60.3%, P < 0.001

Serum

1.82 (1.29, 2.56)

I² = 0.0%, P = 0.704

Detection method:

IHC

1.80 (1.56, 2.07)

I² = 63.4%, P < 0.001

qRT-PCR

1.80 (1.30, 2.50)

I² = 0.0%, P = 0.885

IF

2.45 (1.09, 5.52)

NA

ELISA

1.69 (1.02, 2.81)

NA