Fig. 6

IFIT3 interacts with PD-L1 in HNSC. A and B IHC analysis showed PD-L1 expression was positively correlated with IFIT3. C IFIT3 protein interacting with PD-L1was examined in FaDu and Cal27 cells by co‑ip. D Co-localization based on IF assays, IFIT3 interacted with PD-L1 in the cytoplasm. Scale bar, 20 μm. E Sphere formation experiment was used to detect the effect of PD-L1 on sphere formation ability caused by IFIT3. Scale bar, 200 μm