Fig. 3

IFIT3 enhanced migration and invasion of HNSC cells. A CD44, IFIT3, and PD-L1 expression levels in CD44⁺ and CD44⁻ cells. B Flow cytometry of the distribution of CD44⁺ cells in IFIT3 knockdown and up-regulation in FaDu and Cal 27 cells. C Cells migration at 48 h after scratching in FaDu and Cal27 cells with IFIT3 knockdown were determined by wound-healing assays. Scale bar, 200 μm. D Cells migration at 48 h after scratching in FaDu and Cal27 cells with IFIT3 over-expression were determined by wound-healing assays. Scale bar, 200 μm. E The effect of IFIT3 knockdown on the migration and invasion of FaDu and Cal27 cells. Scale bar, 200 μm. F The effect of IFIT3 over-expression on the migration and invasion of FaDu and Cal27 cells. Scale bar, 200 μm